In the pivotal trial...

Talicia was highly effective as first-line therapy

REFERENCE: 1. Graham DY, Canaan Y, Maher J, Wiener G, Hulten KG, Kalfus IN. Rifabutin-based triple therapy (RHB-105) for Helicobacter pylori eradication:a double-blind, randomized, controlled trial. Ann Intern Med. 2020;172(12):795-802.